Unlock exceptional illumination versatility with the Prizmatix CombiLED high-power multi-wavelength LED illuminator engineered for microscopy and a wide range of scientific applications that demand intense, precisely controlled light across multiple discrete wavelengths. The CombiLED Light Engine enables rapid electronic switching between selected wavelengths, and customers can configure their unit by choosing from a broad selection of LED options spanning UV, visible, NIR, and SWIR to meet specific experimental needs.
This advanced LED illuminator delivers outstanding output power across up to 11 precisely selectable wavelengths, all seamlessly combined and transmitted through a single liquid light guide. The result is uniform, high-intensity illumination at targeted wavelengths without the complexity of multiple fiber inputs. Control options include USB, TTL, and analog input, offering flexibility and integration across diverse scientific setups.
Highly configurable, the CombiLED illuminator can be tailored to deliver narrowband LED wavelengths optimized for specific chromophores or assembled as a broadband LED source using multiple broadband LEDs to generate a white-light spectrum. Customization is streamlined via the Prizmatix Spectra-Viewer, an intuitive online configuration tool.
Key Advantages for Your Research
Instant, Precise Control (Speed & Synchronization)
- Faster Experiments: Thanks to instantaneous ON/OFF switching (via fast TTL control), you can precisely synchronize the light with your camera or external equipment.1 This eliminates motion blur and drastically reduces the overall time needed for complex, multi-frame experiments (like multi-color time-lapses).
- Protect Your Cells: The ability to instantly shutter the light means your live samples are only exposed when the camera is recording, minimizing phototoxicity and photobleaching.
Stability, Power, and Data Quality
- High-Power Performance: Our active cooling and high-current drivers ensure the CombiLED delivers maximum, stable light intensity to your sample, allowing you to use lower exposure times and capture high-quality images.
- Repeatable Results: The advanced 12-Bit digital control (DACs) provides fine, repeatable control over the light output power for every channel. This stability is critical for quantitative fluorescence measurements and reliable data across multiple experiments.
Total Flexibility and Customization
- The Perfect Spectrum: Easily choose the exact LED wavelengths you need from a wide selection to perfectly match your fluorophores (e.g., DAPI, GFP, mCherry, Cy5, etc.). No more settling for wavelengths that don't maximize your signal.
- Simulate Your Setup: Use our helpful online LED Spectra Viewer tool to confirm the compatibility of your existing microscope filters and dichroic mirrors with your chosen CombiLED configuration. You get a customized, optimized system that works seamlessly right out of the box.
Simple Control, Powerful Integration
- Easy-to-Use Software: Control all channels, set protocols, and adjust power levels using the intuitive Multi-LED-Control software for both Windows and Mac operating systems. The standard USB connection to your computer makes connecting and using the software straightforward.
- Advanced Lab Integration: For automation and complex setups, the CombiLED offers dedicated connectivity and tools for fast integration:
USB Computer Control & API: In addition to the easy-to-use software, we provide a Programmer's API (Application Programming Interface) complete with examples in Python, LabView, MATLAB, and many other languages. This enables your team to quickly integrate the CombiLED into automated systems using custom-written software.
TTL Inputs: For seamless, high-speed synchronization with cameras, data acquisition cards, and external microcontrollers.
Analog Input: For controlling power output directly from external devices like function generators (e.g., for dynamic stimulation studies).
Key Features
- Versatile Wavelength Selection: Choose up to 11 individual LED channels with exact wavelengths available from UV through NIR, ensuring a perfect match for your fluorophores, optogenetic tools, or photochemical reactions.
- Intelligent Software Control: Control the system using the Prizmatix Multi-LED-CTRL application available on the Google Chrome browser (for Mac or Windows), with a dedicated desktop application available for Windows users.
- High-Speed, Independent Control: Achieve rapid switching and modulation with dedicated TTL and Analog inputs for every channel, enabling control entirely independent of slow computer processing.
- Optimized for Imaging: Features such as high-speed control enable camera-speed synchronization (essential for high-speed live-cell, ratiometric, and FRET imaging) to precisely capture transient events.
- Precise and Stable Output: Active cooling and advanced 12-bit (4096 levels) drivers ensure the light output is stable and precisely controlled across all channels.
- System Optimization Tools: The included LED-Spectra-Viewer allows for the simulation and optimization of LEDs, dichroic, and bandpass filters.
- Advanced Integration: A complete API with code examples is provided for popular platforms like MATLAB, Python, and LabVIEW for seamless integration into existing setups.
- Optional Enhancements: Includes options for opto-isolated TTL and Analog Inputs for each channel, and pre-installed clean-up filters.
CombiLED Spectra Viewers
The LED-Spectra-Viewer is a powerful online simulation tool that allows users to simulate complex multi-wavelength systems that are coupled through fiber or light guides.We provide a range of templates for CombiLED multi-wavelength systems to simplify the process of designing and implementing these systems. These templates are designed to help streamline the system setup process and make it more efficient.
Optical Specifications
| Optical output | Lightguide (Core diameter 2, 3, 5 mm) |
| Optical output connector | Lightguide adaptor |
| Output power | Depending on LED configuration |
Electrical Specifications
| Connectors for TTL and Analog Input | Optically isolated BNC | |
| Digital modulation (TTL Input 0-5V) | Hz | DC-10000 |
| Analog modulation (Analog Input 0-5V) | Hz | DC-100 |
| Analog power control | % | 0-100 |
| USB Digital control (DAC) | Bit | 12 (~4000 levels) |
| Input Voltage | V | 12 |
General Specifications
| Operation temperature range | °C | 10-35 |
| Storage Temperature range | °C | -10-55 |
| Operating relative humidity (Non condensing) |
% | <90 |
| Enclosure | 19" Rack | |
| Power adaptor safety |  |
Ordering Information
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